CHEMBL404248


SMILES COc1cccc2c1N=C(NCC(F)F)NC2C
InChIKey NWEWYDOUXVOLQN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 255.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.78 5.78 5.78 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database