CHEMBL4066426


SMILES O=S(=O)(c1cccc2ncccc12)N1CCC(CCN2CCN(c3ccc(Cl)c(Cl)c3)CC2)CC1
InChIKey UUNZFDPGHIFDOR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 532.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database