GproteinDb

ephedrine

Agent/drug
Bioactivity

ephedrine

SMILES	CN[C@@H](C)[C@H](O)c1ccccc1
InChIKey	KWGRBVOPPLSCSI-WPRPVWTQSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	165.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central ChEMBL_compound_ids PubChem ChEMBL_compound_ids PubChem PubChem PubChem PubChem GPCRdb

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Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.60	5.60	5.60	Guide to Pharmacology
β₂	ADRB2	Human	Adrenoceptors	A	pKi	8.25	8.25	8.25	Drug Central

Showing 1 to 2 of 2 entries

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Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.90	4.90	4.90	ChEMBL

Showing 1 to 1 of 1 entry

ephedrine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 18

Phase III 0

Phase IV 108

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central ChEMBL_compound_ids PubChem ChEMBL_compound_ids PubChem PubChem PubChem PubChem GPCRdb

Sankey plot

Drug Information

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Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Acute nasopharyngitis	4	CA00	R03C, S01F, R01A, C01C, A08A	0.322
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Allergic rhinitis due to other seasonal allergens	4	CA08.01	R03C, S01F, R01A, C01C, A08A	0.606
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Asthma	4	CA23	R03C, S01F, R01A, C01C, A08A	0.598
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Hypotension, unspecified	4	BA2Z	R03C, S01F, R01A, C01C, A08A	0.603
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Nasal congestion	4	MD11.9	R03C, S01F, R01A, C01C, A08A	0.607
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Obesity, unspecified	4	5B81.Z	R03C, S01F, R01A, C01C, A08A	0.497
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Pain, unspecified	2	MG3Z	R03C, S01F, R01A, C01C, A08A	0.601
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Acute nasopharyngitis	4	CA00	R03C, S01F, R01A, C01C, A08A	0.322
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Allergic rhinitis due to other seasonal allergens	4	CA08.01	R03C, S01F, R01A, C01C, A08A	0.606
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Asthma	4	CA23	R03C, S01F, R01A, C01C, A08A	0.598
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Hypotension, unspecified	4	BA2Z	R03C, S01F, R01A, C01C, A08A	0.603
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Nasal congestion	4	MD11.9	R03C, S01F, R01A, C01C, A08A	0.607
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Obesity, unspecified	4	5B81.Z	R03C, S01F, R01A, C01C, A08A	0.497
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Pain, unspecified	2	MG3Z	R03C, S01F, R01A, C01C, A08A	0.601
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Acute nasopharyngitis	4	CA00	R03C, S01F, R01A, C01C, A08A	0.322
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Allergic rhinitis due to other seasonal allergens	4	CA08.01	R03C, S01F, R01A, C01C, A08A	0.606
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Asthma	4	CA23	R03C, S01F, R01A, C01C, A08A	0.598
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Hypotension, unspecified	4	BA2Z	R03C, S01F, R01A, C01C, A08A	0.603
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Nasal congestion	4	MD11.9	R03C, S01F, R01A, C01C, A08A	0.607
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	A	Obesity, unspecified	4	5B81.Z	R03C, S01F, R01A, C01C, A08A	0.497

Showing 1 to 20 of 63 entries

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Main reference

ephedrine

ephedrine

Chemical Properties

Database connections

Bioactivities

ephedrine

Drug properties

Distribution across phases (no. indications)

Database connections

Sankey plot

Drug Information