CHEMBL4091058


SMILES O=C1CCc2ccccc2N1CCCN1CCN(Cc2ccccc2)CC1
InChIKey RYRTVXCXZPFWGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.22 5.22 5.22 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.58 5.58 5.58 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.17 5.17 5.17 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.32 5.32 5.32 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.83 5.83 5.83 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.58 5.58 5.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database