CHEMBL4093527


SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCc2ccccc2)CC1
InChIKey OJINAULTAMERKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 376.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.12 6.12 6.12 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.7 6.7 6.7 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.3 6.3 6.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.69 6.69 6.69 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.67 8.67 8.67 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.58 6.58 6.58 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.39 6.39 6.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database