CHEMBL410727


SMILES Cc1c(C(=O)NCc2ccc(Cl)c(Cl)c2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C
InChIKey KZNXVRTZOQUIBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 520.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 5.41 5.41 5.41 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.55 7.55 7.55 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.55 7.55 7.55 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.4 5.4 5.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Mouse Cannabinoid A pEC50 7.6 7.6 7.6 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 5.3 5.3 5.3 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 7.3 7.3 7.3 ChEMBL