CHEMBL3990475


SMILES c1ccc2c(c1)CCN(CCCc1nc3ccccc3[nH]1)C2
InChIKey KJBBTZPIHNWETK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 291.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
H1 HRH1 Human Histamine A pKi 6.54 6.54 6.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.04 6.06 6.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database