CHEMBL3991291


SMILES c1ccc2c(c1)CCN(CCCc1nc3ccccc3s1)C2
InChIKey QXUQBHLLDLPFLR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 308.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.39 7.39 7.39 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
H1 HRH1 Human Histamine A pKi 6.08 6.08 6.09 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.74 7.75 7.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database