CHEMBL3991399


SMILES Clc1ccc2sc(CCCCN3CCC4CCCCC4C3)nc2c1
InChIKey IFPGADOWNOXLNQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.36 7.36 7.36 ChEMBL
H1 HRH1 Human Histamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.9 5.92 5.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.93 7.95 7.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database