CHEMBL415310


SMILES CO[C@](C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)(c1ccccc1)C(F)(F)F
InChIKey UYLHHOUQHGFIQB-QNGWXLTQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 684.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pKi 4.89 4.89 4.89 ChEMBL
DP1 PD2R Human Prostanoid A pKi 5.7 5.7 5.7 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 7.92 7.92 7.92 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 4.96 4.96 4.96 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.89 5.89 5.89 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.4 5.4 5.4 ChEMBL
TP TA2R Human Prostanoid A pKi 5.82 5.82 5.82 ChEMBL
FP PF2R Human Prostanoid A pKi 5.42 5.42 5.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database