CHEMBL404888


SMILES COc1cc(CN2CCN(c3ccc(Cl)cc3)CC2)ccc1OCCF
InChIKey VVRAANFGOIKBRD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.07 6.07 6.07 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.24 5.24 5.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.31 5.31 5.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 4.68 4.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database