CHEMBL4061986


SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2cccnc12
InChIKey YRCMSWAPYVIAQO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.24 5.24 5.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.48 7.54 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database