CHEMBL421064


SMILES NCCc1c[nH]c2ccc(OCC(=O)N3CCN(c4ccccc4)CC3)cc12
InChIKey IPCSHRNCCTZQAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.92 9.12 9.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.94 7.96 7.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 9.35 9.35 9.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.3 7.3 7.3 ChEMBL