CHEMBL4102646


SMILES CN1CCN(c2ccc(O)c3c2OCC(=O)N3)CC1
InChIKey MZFAZCYLMYZDDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 263.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.23 7.23 7.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.32 7.32 7.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.2 6.45 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 6.52 6.52 6.52 ChEMBL