GproteinDb

CHEMBL428892

Agent/drug
Bioactivity

CHEMBL428892

SMILES	CSc1ccc2c(c1)[C@@H](N1CCN(C)CC1)Cc1ccccc1S2
InChIKey	RLJFTICUTYVZDG-SFHVURJKSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	356.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	5V54 6WH4

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	9.00	9.00	9.00	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	9.00	9.00	9.00	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	7.02	7.02	7.02	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	6.74	6.74	6.74	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL428892

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	5V54 6WH4

Compound is not listed as a drug.