CHEMBL4291428


SMILES Cc1nc(Nc2ccccc2)sc1C(=O)c1cnc(N)n1-c1ccc(F)cc1
InChIKey NHTCBUYFHZYOOK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 393.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Human Adenosine A pKi 6.72 6.72 6.72 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.09 5.09 5.09 ChEMBL
A1 AA1R Human Adenosine A pKi 4.41 4.41 4.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database