GproteinDb

CHEMBL441618

Agent/drug
Bioactivity

CHEMBL441618

SMILES	CN1CCc2ccccc2Cc2[nH]c3ccccc3c2CC1
InChIKey	YEWGIGCYIAMFMA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	0
Molecular weight (Da)	290.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pKi	7.22	8.35	8.73	ChEMBL
D₁	DRD1	Rat	Dopamine	A	pKi	10.10	10.10	10.10	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	8.22	8.22	8.22	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.35	7.46	7.72	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.39	7.52	7.59	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.97	6.97	6.97	ChEMBL
D₅	DRD5	Human	Dopamine	A	pKi	7.90	8.05	8.12	ChEMBL

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.75	4.78	4.80	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL441618

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.