CHEMBL1160785
SMILES | COc1cc(CCN)ccc1O |
InChIKey | DIVQKHQLANKJQO-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 3 |
Molecular weight (Da) | 167.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Ligand site mutations | D2 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D2 | DRD2 | Rat | Dopamine | A | pKd | 4.03 | 4.04 | 4.06 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
TA1 | TAAR1 | Human | Trace amine | A | pIC50 | 4.67 | 4.67 | 4.67 | ChEMBL |
TA1 | TAAR1 | Human | Trace amine | A | pEC50 | 5.62 | 6.06 | 6.51 | ChEMBL |
M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 7.5 | 7.5 | 7.5 | ChEMBL |
TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 6.9 | 6.9 | 6.9 | ChEMBL |