CHEMBL4469633


SMILES O=c1c(-c2ccc(Cl)cc2)c2n(c(=O)n1CCCCN1CCCC(c3c[nH]c4ccccc34)C1)CCCC2
InChIKey SRUJXUCEPJSKMZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 530.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.78 5.78 5.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database