CHEMBL1256170


SMILES O=C(CCCN1CCC(c2cc3ccc2CCc2ccc(cc2)CC3)CC1)c1cc2ccc1CCc1ccc(cc1)CC2
InChIKey AADWBQLQKGQDIM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 567.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.7 5.7 5.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.72 7.72 7.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.52 7.64 7.77 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database