GproteinDb

CHEMBL450668

Agent/drug
Bioactivity

CHEMBL450668

SMILES	Cc1cc(C[C@@H](NC(=O)N2CCC(N3Cc4cccc(F)c4NC3=O)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cc2cn[nH]c12
InChIKey	HBOINTMVWRSZQS-SSEXGKCCSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	3
Rotatable bonds	6
Molecular weight (Da)	644.4

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

calcitonin-like	CALRL	Human	Calcitonin	B1	pKi	10.89	10.89	10.89	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

calcitonin-like	CALRL	Human	Calcitonin	B1	pEC50	10.46	10.46	10.46	ChEMBL
calcitonin-like	CALRL	Human	Calcitonin	B1	pIC50	10.59	10.59	10.59	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL450668

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.