CHEMBL426863


SMILES O=C(NCCCCN1CCN(c2cccc(F)c2F)CC1)c1cc2ccc1CCc1ccc(cc1)CC2
InChIKey DHFUVVTYPXJZAP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 503.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.72 8.72 8.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 7.19 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database