CHEMBL4534566


SMILES CCc1cc(Cl)c(OC)c(N2CCN(CC(F)CCNC(=O)c3cc4ccccc4[nH]3)CC2)c1
InChIKey CSFWIRRKNFTOOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.18 5.18 5.18 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.02 5.02 5.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 4.68 4.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 6.29 6.29 6.29 ChEMBL