CHEMBL429453


SMILES CCN([C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1)S(=O)(=O)c1ccc(OC)c(OC)c1
InChIKey LVRHAAKFXRNPFH-PSWAGMNNSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 545.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.49 6.49 6.49 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.66 7.66 7.66 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.82 7.82 7.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.95 6.95 6.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database