CHEMBL431354


SMILES Cc1ccc(C)c(N2CCN(CCN3C(=O)CC4(CCCC4)CC3=O)CC2)c1
InChIKey JBWGJAYPUVCZHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 383.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 7.99 7.99 7.99 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.77 6.77 6.77 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.92 6.92 6.92 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.02 7.02 7.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database