CHEMBL456825


SMILES CCCN(CCN1CCN(c2ccccc2)CC1)[C@@H]1CCc2ccc(O)cc2C1
InChIKey POVCSYONXDMZKL-XMMPIXPASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 393.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations D3

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.75 8.75 8.75 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.39 7.39 7.39 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.75 8.75 8.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database