CHEMBL457957


SMILES CN(CCC=C1c2ccccc2CCc2ccccc21)C(=O)Cc1ccc(OCCCN2CCCCC2)cc1
InChIKey FBGLPECKCFZJFU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 522.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.25 6.25 6.25 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
H3 HRH3 Human Histamine A pKi 8.31 8.31 8.31 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.49 6.49 6.49 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.06 6.06 6.06 PDSP Ki database
H1 HRH1 Human Histamine A pKi 6.25 6.25 6.25 PDSP Ki database
H3 HRH3 Human Histamine A pKi 8.31 8.31 8.31 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.04 6.04 6.04 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.49 6.49 6.49 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database