CHEMBL458758


SMILES O=C(NCCCCN1CCN(c2cccc(OCCF)c2)CC1)c1ccc(-n2ccnc2)cc1
InChIKey FVTIZFQEARZLMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 465.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.33 7.33 7.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.71 6.71 6.71 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.71 6.71 6.71 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.33 7.33 7.33 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database