CHEMBL460644


SMILES c1cnc(N2CCN(Cc3c[nH]c4ncccc34)CC2)nc1
InChIKey AWKDBQYMZZKKJX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 294.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.25 7.25 7.25 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.82 5.82 5.82 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 7.25 7.25 7.25 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database