CHEMBL4443848


SMILES CCc1cccc(NC(=O)CN2CCN(c3ccc(Cl)cn3)CC2)c1
InChIKey MJNKHSYDQLOGOJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 358.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.33 4.33 4.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 4.98 5.07 5.15 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.15 4.24 4.33 ChEMBL