CHEMBL464099


SMILES COc1cc2c(cc1O)C[C@H]1c3c(cc(OC)c(OC)c3-2)CCN1C
InChIKey ZFLRVRLYWHNAEC-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.5 6.79 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.8 6.8 6.8 ChEMBL