CHEMBL1258533


SMILES O=C1NCc2ccc(OCCCN3CCN(c4cccc5ccccc45)CC3)cc21
InChIKey HCCHXMMABQRBMV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.83 7.83 7.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.27 10.04 10.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.79 7.79 7.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database