CHEMBL1259190


SMILES CC(C)C(=O)NCc1ccc2c(c1)[C@@H](N1CCN(C)CC1)Cc1ccccc1S2
InChIKey SHVCHMGRIYXVAY-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.7 9.7 9.7 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.8 9.8 9.8 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 9.68 9.68 9.68 ChEMBL
H1 HRH1 Human Histamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.35 8.35 8.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database