CHEMBL464230


SMILES CC1C2Cc3ccc(C(N)=O)cc3C1(C)CCN2CCc1ccccc1
InChIKey RUMQBVLWLNKHTD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.92 8.92 8.92 ChEMBL
κ OPRK Human Opioid A pKi 9.26 9.26 9.26 ChEMBL
μ OPRM Human Opioid A pKi 10.82 10.82 10.82 ChEMBL
μ OPRM Human Opioid A pKi 10.82 10.82 10.82 PDSP Ki database
δ OPRD Human Opioid A pKi 8.92 8.92 8.92 PDSP Ki database
κ OPRK Human Opioid A pKi 9.26 9.26 9.26 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pIC50 6.19 6.19 6.19 ChEMBL
κ OPRK Human Opioid A pEC50 8.36 8.36 8.36 ChEMBL
μ OPRM Human Opioid A pEC50 8.28 8.28 8.28 ChEMBL