CHEMBL4469777


SMILES CCc1cccc(N2CCN(C)CC2)c1Cl
InChIKey WDYXVLOKALEPOS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 238.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.87 7.87 7.87 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.49 8.49 8.49 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.24 7.24 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.15 6.15 6.15 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.56 7.56 7.56 ChEMBL