CHEMBL4473792


SMILES Cc1ccc(C2CCN(CC(=O)Nc3cccc(C)c3)CC2)cc1
InChIKey AXJOWWAHGHUVEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.43 5.43 5.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.11 5.11 5.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 5.13 5.32 5.51 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.05 4.2 4.35 ChEMBL