CHEMBL4474014


SMILES Fc1ccc2c(c1)CC(CCN1CCCN(c3ccccn3)CC1)C2
InChIKey RVMUAKCKCUJBKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.1 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.21 6.22 6.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.22 6.22 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database