CHEMBL472810


SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C3C4C(=O)CC(OC(C)=O)(CC4(C)C)C3C2=O)CC1
InChIKey DPWUKQLYJJZSJQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 525.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database