CHEMBL4745885


SMILES COC1CN(C(=O)CCN2CCCc3ccccc32)C1
InChIKey CGOUBIILQTVZLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 274.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 4.8 4.8 4.8 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 4.49 4.49 4.49 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.45 5.45 5.45 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 4.76 4.76 4.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 4.69 4.69 4.69 ChEMBL