CHEMBL4754138


SMILES O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cccc2ccccc12
InChIKey PUHAZBKUVIJPMC-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.75 8.75 8.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.35 9.35 9.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database