CHEMBL4533305


SMILES O=C(CCCN1CCCN(c2ccccn2)CC1)c1ccc(F)cc1
InChIKey YZWJNFUQGOYUQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.81 6.03 6.25 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.59 6.59 6.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.46 5.46 5.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.91 8.91 8.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.72 6.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database