CHEMBL1270282


SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc13
InChIKey NFXFNBIPWUYEIM-WXFUMESZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 372.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 7.67 7.67 7.67 ChEMBL
δ OPRD Mouse Opioid A pKi 9.8 9.8 9.8 ChEMBL
κ OPRK Guinea pig Opioid A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.28 9.28 9.28 ChEMBL
κ OPRK Human Opioid A pEC50 6.31 6.31 6.31 ChEMBL
μ OPRM Human Opioid A pEC50 6.63 6.63 6.63 ChEMBL