CHEMBL1269776


SMILES Cc1c(C(=O)NCCCCCCCCCCCN(C)CCCCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1
InChIKey JTLZKYIJFISRSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 26
Molecular weight (Da) 731.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.37 6.37 6.37 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.83 8.04 8.26 ChEMBL
CB1 CNR1 Human Cannabinoid A pKd 7.63 7.63 7.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pEC50 5.06 5.06 5.06 ChEMBL