CHEMBL4573441


SMILES O=C(CCCN1CCN(c2ccc(Cl)cn2)CC1)c1ccc(F)cc1
InChIKey MXKZBMGRCYCKSV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.29 8.29 8.29 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.06 7.06 7.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database