CHEMBL4582096


SMILES COc1ccc(N(Cc2ccc(F)cc2)NC(=O)NCCCN2CCN(c3ccccc3OC)CC2)cc1
InChIKey SKNVJEZUCGHGRG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 521.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.8 6.88 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database