CHEMBL4795995


SMILES O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cc2ccccc2s1
InChIKey HEEFMGUIOXQXAL-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 441.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.32 8.32 8.32 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.49 8.49 8.49 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.5 8.5 8.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.35 9.35 9.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database