CHEMBL4802932


SMILES CN(C)c1ccc2c(-c3ccc(C(=O)NCCN4CCN(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc76)CC5)CC4)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1
InChIKey XJFLDBYRKJAMIK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 930.5

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.75 6.75 6.75 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.01 9.01 9.01 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.09 7.09 7.09 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.86 9.04 9.22 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.59 9.11 9.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database