CHEMBL4598389


SMILES CCCN(CCCSc1nnc(-c2ccccc2)n1C)CC1CC1c1cc(Cl)ccc1OC
InChIKey RAPBVKVRRNGNRM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.89 6.89 6.89 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.63 6.63 6.63 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database