CHEMBL4857665


SMILES O=C1c2ccc(Cl)cc2CC1CCCCN1CCN(c2ccccn2)CC1
InChIKey YQSDVKUMLQLWSX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.82 7.83 7.83 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.43 6.44 6.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.36 8.38 8.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.36 6.38 6.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.93 5.97 6.01 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database