GR 196429


SMILES CC(=O)NCCN1CCc2c1c1CCOc1cc2
InChIKey LTYWTNUOUBBVNZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 8.64 9.25 9.85 PDSP Ki database
MT2 MTR1B Human Melatonin A pKi 9.7 9.75 9.8 Guide to Pharmacology
MT1 MTR1A Human Melatonin A pKi 9.4 9.65 9.9 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.32 9.56 9.8 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database